Events

There is substantial individual variability in how individuals respond to stress, and a major predictor of this variance is the prior experience of stress. Here, I’ll share data showing that prior stress inflates negative valence signals in an amygdala-hypothalamic circuit and increases stress vulnerability.

How does the brain maintain stable internal representations of the world while also remaining flexible enough to learn, adapt, and predict the future?  This is a central question in systems neuroscience.  In this talk, I will present recent work from my lab that addresses this problem at both the level of network dynamics and the […]

This presentation will review the need for a precision medicine approach to opioid withdrawal and illustrate how variability in withdrawal symptom expression would inform novel treatment strategies. Differences in withdrawal […]

The talk will undertake an overview of the physiology of the human dying process as an in vivo model of brain ischemia physiology. The talk will cover the feasibility of […]

Human cognition and mental health do not arise from the brain alone, but from continuous interactions among people, bodies, and social environments. This talk introduces a multi-brain perspective on neuroscience […]

Neurons are defined by their remarkable polarity, a feature that is highly conserved across most nervous systems. A key neuronal structure, the axon initial segment (AIS), is essential for establishing […]

A key behavioral characteristic of autistic individuals is difficulty with mentalization—the ability to understand and respond to the mental states of others. While these difficulties have important social and clinical consequences, the […]

I will be presenting data on an animal model of Multiple Sclerosis (MS) progression, how we have used this model to better understand disease progression and to understand how MS […]

Title: Capabilities and Collaborations: Charting the NINC’s second decade Presented by: Jeff LeDue The NeuroImaging and NeuroComputation (NINC) core has grown rapidly over its first decade adding many new instruments […]

This talk will introduce emerging roles for microglia and discrete innate immune signaling pathways in the pathogenesis of Alzheimer’s disease, tauopathies, and brain injury.  

A large body of recent work has focused on the problem of inferring neural population dynamics from recordings of neural activity. However, these models typically ignore the fact that the […]

Dr. Bolton will discuss how early-life adversity impacts brain development in the context of psychiatric disorders, with a focus on the role of microglia in the synaptic rewiring of stress-sensitive […]