Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Dr. Michael Kobor is a Professor in the Department of Medical Genetics at the University of British Columbia (UBC) and The Edwin S.H. Leong UBC Chair in Healthy Aging—a UBC President’s Excellence Chair. He began his academic studies in his native Germany, before coming to Canada to complete his PhD in Medical Genetics under Dr. Jack Greenblatt at the University of Toronto. He then completed postdoctoral training as a Human Frontier Science Program Fellow with Dr. Jasper Rine at the […]

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Innate immunity plays a pivotal role in the pathophysiology of multiple sclerosis (MS) and important cell types involved in this process are CNS resident monocytes (microglia) and blood-derived macrophages. Chronic CNS inflammation in the MS lesion is maintained, in part, with iron-laden pro-inflammatory microglia/macrophages (m/M) at the rim of chronic active MS lesions. These lesions are felt to contribute to a more aggressive phenotype of the disease; thus, represents a novel treatment target to reduce disease progression in MS. Identification […]

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Dr. Oka will discuss how innate instinct to consume water and salt is regulated through body-brain interactions.

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Objectives: 1) Neural stem cells build and regenerate the brain in part by forming oligodendrocytes, the myelinating cells of the central nervous system 2) Endogenous neural stem cells can be engaged in mouse models of neurodegenerative disorders for brain remyelination 3) Neurodegenerative disorders may have a neurodevelopmental origin, and neurodevelopmental disorders may have a neurodegenerative component.

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Decision-making is an unobservable cognitive process. This makes it challenging to investigate the underlying neuronal mechanisms. This lecture will discuss how techniques borrowed from the brain-machine interface field, such as decoding population activity and closed-loop control, can be used to understand how cognitive processes such as decision-making are implemented at the neuronal level. This approach could also lead to the development of novel devices for the treatment of neuropsychiatric disorders that involve impaired decision-making.

Dr. Annie Ciernia: "Mechanisms of Peripheral Lipopolysaccharide Induced Brain Inflammation" Dr. Paul van Donkelaar: "Characterizing tau pathology in survivors of intimate partner violence-related traumatic brain injury" Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258

Neha Suvindran: "Reimagining Neuro-Bioelectronic Systems: Sustainable, Stable and Self-healing Fiber Electrodes" Drs. Rebecca Todd and Stan Floresco: "Translation Investigation of Neurophysiological Substrates of Active and inhibitory Avoidance in healthy and depressed populations." Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Learned fear often relapses after extinction, suggesting that extinction training generates a new memory that coexists with the original fear memory. Recent work from our lab has identified the hippocampus as a region where such fear and extinction memories exist and compete for expression. In this talk I will discuss recent work in our lab in which we have used activity-dependent neural tagging in mice to identify, manipulate, and characterize the cellular mechanisms of these hippocampal fear and extinction memories. […]

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Puberty and ensuing adolescence represent a time when the brain is rapidly developing and is sensitive to environmental stimuli. This lecture will discuss evidence that pubertal adversity puts females at risk for altered stress responding and maternal behavior later in life. Evidence will be presented that pubertal stress leads to an enduring programmatic event in the chromatin landscape in several brain regions, which may underlie both the lasting transcriptomic and behavioral consequences of pubertal stress.