Dr. Ryan McLaughlin: Lost in Translation: Leveraging Preclinical Models to Interrogate Effects of Developmental Cannabis Exposure

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Maternal cannabis use is a growing public health concern, yet the long-term effects of prenatal cannabis exposure remain elusive. Our understanding of how prenatal cannabis exposure affects the brain and behavior is critically informed by preclinical animal models that capture core components of human cannabis use. To this end, our laboratory and others have recently developed more translational models of cannabis use that have potential to provide unprecedented insight into the protracted effects of cannabis exposure during sensitive developmental stages.  In this presentation, I will describe recent data from our laboratory using a novel model of cannabis vapor self-administration in […]


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Drs. George Augustine, Lim Kah Leong and Nagaendran Kandiah

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Professor George Augustine –  Nanyang Technological University, Singapore Talk Title: "Synapses and synaptic circuits in health and disease" Professor Lim Kah Leong – Nanyang Technological University, Singapore Talk Title: "Neuroprotective and neurorestorative strategies for Parkinson’s disease" Professor Nagaendran Kandiah –  Nanyang Technological University, Singapore Talk Title: "Fluid biomarker and neuroimaging profile of mild cognitive impairment in Southeast Asians" Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589


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Dr. Fabian Voigt: Expanding the optical bag of tricks for neuroscience 

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Seeing is believing and thus, optical imaging techniques are extremely useful to study brain structure and function. I will present two projects aimed at providing the neuroscience community with better imaging instrumentation. In the first part, I will introduce the mesoSPIM ( http://mesospim.org/ ), an open-source light-sheet microscope that is optimized for fast imaging of large cleared tissue samples at 5-7 µm isotropic resolution. Since 2015, the mesoSPIM evolved from a crude prototype into a highly capable instrument and we […]


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Abusing dopamine enhancing drugs: A case study

DMCBH Room 3402 2215 Wesbrook Mall, Vancouver

This month, Dr. Andrew Howard from the Neuropsychiatry group in the Department of Psychiatry will present on "Abusing dopamine enhancing drugs: A case study." Zoom link if unable to attend in person:  https://ubc.zoom.us/j/5747966049?pwd=N1ppY2tUS3o4bk9vTkFSTzBna3k0Zz09 Meeting ID: 574 796 6049 Passcode: 052059


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Dr. Michael Kobor: Epigenetics and the Human Life Course

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Dr. Michael Kobor is a Professor in the Department of Medical Genetics at the University of British Columbia (UBC) and The Edwin S.H. Leong UBC Chair in Healthy Aging—a UBC President’s Excellence Chair. He began his academic studies in his native Germany, before coming to Canada to complete his PhD in Medical Genetics under Dr. Jack Greenblatt at the University of Toronto. He then completed postdoctoral training as a Human Frontier Science Program Fellow with Dr. Jasper Rine at the […]


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Dr. Susan Gauthier: Imaging a new treatment target in Multiple Sclerosis: Chronic Active Lesions

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Innate immunity plays a pivotal role in the pathophysiology of multiple sclerosis (MS) and important cell types involved in this process are CNS resident monocytes (microglia) and blood-derived macrophages. Chronic CNS inflammation in the MS lesion is maintained, in part, with iron-laden pro-inflammatory microglia/macrophages (m/M) at the rim of chronic active MS lesions. These lesions are felt to contribute to a more aggressive phenotype of the disease; thus, represents a novel treatment target to reduce disease progression in MS. Identification […]


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Dr. Yuki Oka: Regulation of fluid homeostasis through gut-brain signaling

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Dr. Oka will discuss how innate instinct to consume water and salt is regulated through body-brain interactions.


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Data Deposit Basics

Online

Please join us at Databinge on January 27th for “Data Deposit Basics” with Eugene Barsky. Eugene is the UBC Library’s Research Data Management Librarian and he will cover file naming, folder structures, README files, metadata, PIDs, Data Management Plans and FAIR principles. Contact Jeff LeDue (jledue@mail.ubc.ca) with any questions. Zoom link


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Dr. Anastassia Voronova: (Re)generating oligodendrocytes in the developing and degenerating brain: a neural stem cell perspective

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Objectives: 1) Neural stem cells build and regenerate the brain in part by forming oligodendrocytes, the myelinating cells of the central nervous system 2) Endogenous neural stem cells can be engaged in mouse models of neurodegenerative disorders for brain remyelination 3) Neurodegenerative disorders may have a neurodevelopmental origin, and neurodevelopmental disorders may have a neurodegenerative component.


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Dr. Joni Wallis: Neuronal mechanisms of value-based decision-making: a brain-machine interface approach

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Decision-making is an unobservable cognitive process. This makes it challenging to investigate the underlying neuronal mechanisms. This lecture will discuss how techniques borrowed from the brain-machine interface field, such as decoding population activity and closed-loop control, can be used to understand how cognitive processes such as decision-making are implemented at the neuronal level. This approach could also lead to the development of novel devices for the treatment of neuropsychiatric disorders that involve impaired decision-making.


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Using fMRI to model representational content in a translational context

DMCBH Room 3402 2215 Wesbrook Mall, Vancouver

This month, Prof. Beck Todd from the Department of Psychology will present on "Using fMRI to model representational content in a translational context." Zoom link if unable to attend in person:  https://ubc.zoom.us/j/5747966049?pwd=N1ppY2tUS3o4bk9vTkFSTzBna3k0Zz09 Meeting ID: 574 796 6049 Passcode: 052059


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UBC Kickstart Updates: Drs. Annie Ciernia and Paul van Donkelaar

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Dr. Annie Ciernia: "Mechanisms of Peripheral Lipopolysaccharide Induced Brain Inflammation" Dr. Paul van Donkelaar: "Characterizing tau pathology in survivors of intimate partner violence-related traumatic brain injury" Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258


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