Events

Combining open-ended interviews (outside the scanner) with structural, trial-by-trial, and resting-state functional MRI neuroimaging, we examined real-time functional neural dynamics underlying diverse urban mid-adolescents’ cognitive and emotional engagement with compelling […]

Successful pursuit of reinforcers requires the generation of predictions and evaluation of outcomes. Midbrain dopamine neurons and their projections to the striatum are thought to be critical for these processes. […]

The human brain has the remarkable capacity to transport the self into the past and future. While previously thought of as distinct functions, recent research has shown that memory for […]

Understanding how the brain encodes, stores, and uses information is a central goal of neuroscience. Many neuropsychiatric and neurodegenerative disorders, including autism spectrum disorder, post-traumatic stress disorder (PTSD), and Alzheimer’s […]

Dr. Mayo will talk about studies involving animal-to-human translational work highlighting how endocannabinoid function regulates stress reactivity and fear learning, leveraging human behavioral pharmacology and neuroimaging. She will also highlight outcomes from a recent clinical trial exploring how augmenting cannabinoid function impacts clinical, behavioral, and neural measures in people with PTSD.

Natural visual processing entails a complex interplay between sensory input, behavioral context, and on-going brain dynamics. Our lab seeks to understand how these processes give rise to goal-directed visual behaviors, by exploring the neural circuits mediating ethologically relevant behaviors that laboratory mice perform, including prey capture and distance estimation. We are also implementing novel experimental […]

This talk will highlight recent efforts to generate and analyze spatially resolved molecular datasets to better understand structure–function relationships in the human brain, particularly in the context of complex brain disorders. While single-cell and single-nucleus sequencing approaches have rapidly advanced our ability to define molecularly distinct cell populations, these methods often lack the spatial and […]

Despite decades of research on the properties of ventral tegmental area (VTA) dopamine neurons, the precise information encoded by these cells in reward learning and motivated behavior remains uncertain. In […]

There is substantial individual variability in how individuals respond to stress, and a major predictor of this variance is the prior experience of stress. Here, I’ll share data showing that […]

How does the brain maintain stable internal representations of the world while also remaining flexible enough to learn, adapt, and predict the future?  This is a central question in systems neuroscience.  In this talk, I will present recent work from my lab that addresses this problem at both the level of network dynamics and the […]