Events

Neurons are defined by their remarkable polarity, a feature that is highly conserved across most nervous systems. A key neuronal structure, the axon initial segment (AIS), is essential for establishing and maintaining a functional, polarized neuronal architecture. As such, defects in the AIS and a loss of polarity are associated with neurological dysfunction and numerous […]

A key behavioral characteristic of autistic individuals is difficulty with mentalization—the ability to understand and respond to the mental states of others. While these difficulties have important social and clinical consequences, the neurocognitive mechanisms underlying them remain poorly understood. In this presentation, I will argue that one reason for this lack of progress is the limitation of standard experimental approaches […]

I will be presenting data on an animal model of Multiple Sclerosis (MS) progression, how we have used this model to better understand disease progression and to understand how MS treatments impact this process. By going back and forth between the animal model and MS tissues, we have learned about what can trigger so-called “compartmentalized […]