Dr. Kim Green: Exploring microglia function in the healthy and Alzheimer’s disease brain

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Microglia are the primary immune cell of the brain, but have roles outside of immunity as well as being implicated in the pathogenesis of many CNS disorders. Here I will show how we can use CSF1R inhibitors to control the microglial population in vivo, and elucidate their functions in both the homeostatic and disease brains. […]


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Dr. Eugenii A. (Ilan) Rabiner: Molecular Imaging in CNS drug development

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Over the past 25 years the costs of drug development have been rising steeply, with later phases being particularly resource intensive. Molecular imaging (primarily PET) has become an indispensable tool in early phase drug development, […]


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Dr. Eric Yttri: Understanding brain-wide circuit dynamics underlying learned and spontaneous behavior with B-SOiD

For decades, neuroscience has focused almost exclusively on stereotyped, reductionist, and over-trained behaviors due to their ease of study. In contrast, naturalistic behavior provides a rich diversity of movements, but this feature also largely precludes it from quantification and use. Recent advances in computer vision have enabled automatic tracking of the position of body parts - but position […]


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Dr. Anthony Filiano: Regulating the Brain from Its Borders

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 The CNS is an immune-privileged organ, yet we know that peripheral immunity is critical for proper brain function. Here we will discuss cell communications in the meninges that regulate patrolling T cells and how the […]


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Dr. Mihaela Iordanova: Neurobiology of secondary fear triggers

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 The study of how the brain regulates learned fear has been fundamental to understanding brain function and has served as a pre-clinical animal model for fear- and anxiety-related disorders in humans. The current model has […]


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Dr. Ryan McLaughlin: Lost in Translation: Leveraging Preclinical Models to Interrogate Effects of Developmental Cannabis Exposure

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Maternal cannabis use is a growing public health concern, yet the long-term effects of prenatal cannabis exposure remain elusive. Our understanding of how prenatal cannabis exposure affects the brain and behavior is critically informed by preclinical animal models that capture core components of human cannabis use. To this end, our laboratory and others have recently […]


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Drs. George Augustine, Lim Kah Leong and Nagaendran Kandiah

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Professor George Augustine –  Nanyang Technological University, Singapore Talk Title: "Synapses and synaptic circuits in health and disease" Professor Lim Kah Leong – Nanyang Technological University, Singapore Talk Title: "Neuroprotective and neurorestorative strategies for Parkinson’s disease" Professor Nagaendran Kandiah –  Nanyang Technological University, Singapore Talk Title: "Fluid biomarker and neuroimaging profile of mild cognitive impairment […]


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Dr. Fabian Voigt: Expanding the optical bag of tricks for neuroscience 

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Seeing is believing and thus, optical imaging techniques are extremely useful to study brain structure and function. I will present two projects aimed at providing the neuroscience community with better imaging instrumentation. In the first […]


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Dr. Michael Kobor: Epigenetics and the Human Life Course

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Dr. Michael Kobor is a Professor in the Department of Medical Genetics at the University of British Columbia (UBC) and The Edwin S.H. Leong UBC Chair in Healthy Aging—a UBC President’s Excellence Chair. He began […]


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Dr. Susan Gauthier: Imaging a new treatment target in Multiple Sclerosis: Chronic Active Lesions

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Innate immunity plays a pivotal role in the pathophysiology of multiple sclerosis (MS) and important cell types involved in this process are CNS resident monocytes (microglia) and blood-derived macrophages. Chronic CNS inflammation in the MS […]


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Dr. Yuki Oka: Regulation of fluid homeostasis through gut-brain signaling

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Dr. Oka will discuss how innate instinct to consume water and salt is regulated through body-brain interactions.


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Dr. Anastassia Voronova: (Re)generating oligodendrocytes in the developing and degenerating brain: a neural stem cell perspective

Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, Vancouver

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Objectives: 1) Neural stem cells build and regenerate the brain in part by forming oligodendrocytes, the myelinating cells of the central nervous system 2) Endogenous neural stem cells can be engaged in mouse models of neurodegenerative disorders for […]


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Neuroscience Research Colloquium

The Neuroscience Research Colloquium (NRC), is a series of lectures featuring local and international neuroscientists.