Events

I will be presenting data on an animal model of Multiple Sclerosis (MS) progression, how we have used this model to better understand disease progression and to understand how MS treatments impact this process. By going back and forth between the animal model and MS tissues, we have learned about what can trigger so-called “compartmentalized […]

Title: Capabilities and Collaborations: Charting the NINC’s second decade Presented by: Jeff LeDue The NeuroImaging and NeuroComputation (NINC) core has grown rapidly over its first decade adding many new instruments which extend our community’s capabilities for measuring key aspects of brain structure and function.  This presentation will highlight these new instruments, including our 3-photon microscope, […]

This talk will introduce emerging roles for microglia and discrete innate immune signaling pathways in the pathogenesis of Alzheimer’s disease, tauopathies, and brain injury.  

A large body of recent work has focused on the problem of inferring neural population dynamics from recordings of neural activity. However, these models typically ignore the fact that the […]

Dr. Bolton will discuss how early-life adversity impacts brain development in the context of psychiatric disorders, with a focus on the role of microglia in the synaptic rewiring of stress-sensitive […]

Bioelectronic implants for brain stimulation provide critical tools for treating brain diseases as well as investigating fundamental biology but require invasive surgery. In this talk I will discuss a new […]

I will present work we have pursued to identify key mechanisms explaining aberrant pain processing by the nervous system as well as co-morbidities that develop from sustained pain hypersensitivity. This […]

The human brain comprises billions of neurons that communicate primarily through chemical synapses by releasing diverse neuromodulators, which regulate perception, movement, learning, and memory. Dissecting the neural mechanisms in both […]

TDP-43 protein aggregation is a pathological hallmark of amyotrophic lateral sclerosis (ALS). In this talk, Dr. Michael Strong will discuss the discovery of NF242, an N-terminal fragment of the RNA-binding […]

The head-direction (HD) circuit, an upstream provider of orientation signals for navigation, maintains coherent internal orientation memory that stays stable within each environment for weeks. During non-REM sleep, when hippocampal […]