Dr. Kathleen Morrison: Role for chromatin remodeling in the lifelong consequences of pubertal adversity on the brain and behavior
Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, VancouverZoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Puberty and ensuing adolescence represent a time when the brain is rapidly developing and is sensitive to environmental stimuli. This lecture will discuss evidence that pubertal adversity puts females at risk for altered stress responding and maternal behavior later in life. Evidence will be presented that pubertal stress leads to an enduring programmatic event in the chromatin landscape in several brain regions, which may underlie both the lasting transcriptomic and behavioral consequences of pubertal stress.