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How curiosity shaped Dr. Callista Yee’s path to neuroscience

As a child, Dr. Callista Yee wanted to become an oncologist. Her older brother had childhood cancer and watching the physicians who cared for him inspired her to pursue a career where she could make a difference in people’s lives. “I wanted to pay that forward,” she says. “And so I developed an interest in STEM and medicine from a…

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Dr. Michael J. Strong: The discovery of NF242 as a potential biotherapeutic for ALS: when a little competition is a good thing

October 23

2215 Wesbrook Mall
Vancouver, British Columbia V6T 1Z3 Canada

TDP-43 protein aggregation is a pathological hallmark of amyotrophic lateral sclerosis (ALS). In this talk, Dr. Michael Strong will discuss the discovery of NF242, an N-terminal fragment of the RNA-binding protein RGNEF that competes for interactions with TDP-43 and reduces its toxicity in experimental models of ALS. Dr. Strong will describe the development of NF242 as a potential biotherapeutic and…

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