-
Dr. Adrien Peyrache: Orienting memory during wake and sleep
Dr. Adrien Peyrache: Orienting memory during wake and sleep
The head-direction (HD) circuit, an upstream provider of orientation signals for navigation, maintains coherent internal orientation memory that stays stable within each environment for weeks. During non-REM sleep, when hippocampal trajectories are replayed for memory formation, HD cells remain coordinated and directly influence this hippocampal replay. This suggests the HD system conveys a "virtual" orientation […]