Check out some of the papers that were published by DMCBH members in the past few weeks:
Luke Clark: Serotonergic and dopaminergic control of impulsivity in gambling disorder
Journal: Addiction Biology
Gambling disorder (GD) is a major public health issue. The disorder is often characterized by elevated impulsivity with evidence from analogous substance use disorders underlining prominent roles of brain monoamines in addiction susceptibility and outcome. Critically, GD allows the study of addiction mechanisms without the confounder of the effects of chronic substances. This study assessed the roles of striatal dopamine transporter binding and extrastriatal serotonin transporter binding in GD as a function of impulsivity using (123I)FP-CIT SPECT imaging in 20 older adults with GD and 40 non-GD age- and sex-matched controls.
Fidel Vila-Rodriguez: Brain fog fix: case report of repetitive transcranial magnetic stimulation for treatment of post-COVID-19 cognitive impairment and depressive symptoms
Project: Central Autonomic Network in Depression
This is a case report about the successful use of repetitive transcranial magnetic stimulation (rTMS) to address brain fog associated with post-COVID-19 cognitive impairment and depressive symptoms. The left dorsolateral prefrontal cortex (DLPFC) is one of the main stimulation targets for rTMS due to its association with various executive function processes including planning, attention, and working memory.
Jehannine Austin: Evaluating treatment outcomes in pharmacogenomic-guided care for major depression: A rapid review and meta-analysis
Journal: Psychiatry Research
Pharmacogenomic (PGx) testing may increase the probability of remission and response in patients with major depressive disorder (MDD) undergoing pharmacotherapy. Given the potential implications of these outcomes and recent proliferation of PGx studies, researchers conducted a systematic review to evaluate the effectiveness of PGx testing on clinical outcomes in patients with MDD as compared to treatment as usual.
Robin Hsiung: White-matter abnormalities in presymptomatic GRN and C9orf72 mutation carriers
Journal: Brain Communications
Brain imaging abnormalities that develop before dementia onset in mutation carriers may serve as proxies for the presymptomatic stages of familial frontotemporal dementia due to a genetic cause. The objective for this study was to investigate brain MRI-based white-matter changes in predementia participants carrying mutations in C9orf72 or GRN genes.