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A critical step in neural circuit assembly is the integration of inhibitory interneurons with exquisite specificity in their numbers, distribution and synaptic connectivity. Our lab aims to identify cellular and molecular mechanisms that generate interneuron diversity and specify their precise wiring patterns in retinal and brain circuits in mouse models. I will present our work on the roles of Cadherin superfamily recognition molecules in regulating inhibitory interneuron development and wiring, as well as a toolkit we are developing to map trans-neuronal interactions and connectivity in vivo.