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X-WR-CALDESC:Events for Djavad Mowafaghian Centre for Brain Health | DMCBH
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DTSTART;TZID=America/Vancouver:20220204T110000
DTEND;TZID=America/Vancouver:20220204T120000
DTSTAMP:20260501T143539
CREATED:20210722T000000Z
LAST-MODIFIED:20220211T005611Z
UID:3738-1643972400-1643976000@www.centreforbrainhealth.ca
SUMMARY:Dr. John Kramer: Translational Research in Acute Spinal Cord Injury
DESCRIPTION:This event will be held virtually: \nZoom link
URL:https://www.centreforbrainhealth.ca/events/dr-john-kramer/
LOCATION:Online
CATEGORIES:Neuroscience Research Colloquium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20220211T110000
DTEND;TZID=America/Vancouver:20220211T120000
DTSTAMP:20260501T143539
CREATED:20211016T053047Z
LAST-MODIFIED:20220211T005633Z
UID:7205-1644577200-1644580800@www.centreforbrainhealth.ca
SUMMARY:Dr. Cheryl Wellington: Fluid biomarkers in neurology: Clinical and translational studies
DESCRIPTION:Diseases of the brain are among the most challenging disorders to diagnose and treat. Unlike cancer\, where human tissue biopsy specimens are routinely collected\, brain disorders lack routine access to specimens that are essential to make progress in understanding pathophysiology and developing effective treatments. Currently\, most brain diseases are studied in living patients using neuroimaging or invasive cerebrospinal fluid (CSF) collection. New technologies now allow brain-derived substances to be measured in blood\, which is revolutionizing the field of neurology. The Wellington lab is currently collaborating with several local neurologists to develop and validate blood biomarkers for several acute and chronic neurological conditions. Highlights of our studies in Alzheimer’s Disease\, spinal cord injury and hypoxic ischemic brain injury will be presented. We are also present our program to develop and validate parallel assays that work in rodents to better understand the translational relevance of studies in animal models. \n\nZoom option if unable to attend in person\nZoom link here (click on “Join a meeting”)\nMeeting ID: 99412 188589\nPasscode: 188589
URL:https://www.centreforbrainhealth.ca/events/dr-cheryl-wellington/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20220217T133000
DTEND;TZID=UTC:20220217T143000
DTSTAMP:20260501T143539
CREATED:20220117T233703Z
LAST-MODIFIED:20220119T193905Z
UID:8025-1645104600-1645108200@www.centreforbrainhealth.ca
SUMMARY:Open science: From genes to affordable medicines
DESCRIPTION:Dr. Edwards has offered to meet with researchers throughout the day on Feb 17 to discuss open science. If you are interested\, please reach out to Paul Pavlidis (paul@msl.ubc.cs).  Trainees are welcome to meet with Dr. Edwards after his talk from 2:30-3:30pm. \nPlease note this event is scheduled to be in person. If you cannot attend\, below is the Zoom information:  \n\nZoom link: https://ubc.zoom.us/j/91770392007?\nPasscode: 392007\n\nSociety has decided that the development of new medicines is the role of the private sector\, and supports this decision with a range of policies. \nAnd while this drug development system has produced remarkable discoveries\, the “maximize profit” structure of the ecosystem has consequences.  Some diseases are not explored because of a lack of market incentive\, and access to new medicines is not equitable. \nWithin this backdrop\, Dr. Edwards will argue that universities\, through their tech transfer policies\, are complicit in this inequitable system\, and we should develop new policies and models in which equitable access is the priority. \nOpen science is a tactic to this end\, and Dr. Edwards will describe several drug discovery projects that that have been initiated under the open science framework\, as well as the legal and business frameworks that we are developing to ensure we get the drugs to market.
URL:https://www.centreforbrainhealth.ca/events/open-science-from-genes-to-affordable-medicines/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
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DTSTART;TZID=America/Vancouver:20220218T110000
DTEND;TZID=America/Vancouver:20220218T120000
DTSTAMP:20260501T143539
CREATED:20210722T000000Z
LAST-MODIFIED:20220301T222335Z
UID:3737-1645182000-1645185600@www.centreforbrainhealth.ca
SUMMARY:Dr. Jorn Diedrichsen: Exploring the role of the human cerebellum across functional domains
DESCRIPTION:The cerebellum has evolved to support basic sensory-motor functions. In the human brain\, the cerebellar circuitry has dramatically expanded and contributes to virtually every cognitive function\, including working memory\, language\, and social cognition. Given its uniform cytoarchitecture\, it has long been hypothesized that the cerebellar circuit performs a common computation across all these functional domains. But what is this elusive transform? To ultimately answer this question we require a better understanding of the functional diversity of the cerebellum\, it’s connectivity to the neocortex\, and the relationship between cortical and cerebellar processes in each functional domain. I will present results from a number functional neuroimaging studies to characterize cerebellar function across cognitive domains to start to address these questions in a systematic fashion. \nRudy North Lecture Theatre “Live” Screening\nZoom option if unable to attend in person: \n\nZoom link here (click on “Join a meeting”)\nMeeting ID: 99412 188589\nPasscode: 188589
URL:https://www.centreforbrainhealth.ca/events/dr-jorn-diedrichsen/
LOCATION:British Columbia
CATEGORIES:Neuroscience Research Colloquium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220228T120000
DTEND;TZID=America/Los_Angeles:20220228T130000
DTSTAMP:20260501T143539
CREATED:20220223T005231Z
LAST-MODIFIED:20220228T181521Z
UID:8303-1646049600-1646053200@www.centreforbrainhealth.ca
SUMMARY:He Tian candidate presentation
DESCRIPTION:Please note this event is postponed until 12:00pm due to flight delays. \nThe brain encodes and processes information through the dynamic membrane voltage of neurons. However\, in vivo electrophysiology\, i.e.\, the study of the membrane voltage of individual cells in live animals\, has been a major challenge for neuroscience. In this seminar\, I will present voltage imaging\, an emerging technology using genetically encoded voltage indicators (GEVIs) to visualize the membrane voltage dynamics of cells. Voltage imaging can be combined with optogenetic stimulation to enable “all-optical electrophysiology”\, a technology that enabled cell membrane voltage to be simultaneously recorded and perturbed with light\, opening a path for high-throughput electrophysiology study in live animals. Thus far\, the performance of GEVIs has been a bottleneck for many in vivo applications. I will describe my directed evolution effort to improve far-red GEVIs. In order to optimize the transient voltage response of this biosensor\, I developed a novel video-based pooled screening platform that enabled thousands of genetic variants to be screened expeditiously. Using this platform\, I developed far-red GEVIs with improved signal-to-noise ratios and kinetics. Importantly\, this platform may be adapted for many types of genetic screens where optical readouts are required. I will discuss the application of these new GEVIs for drug screening and tracking electric signal propagation within neurons. In particular\, I will demonstrate how to use voltage imaging and all-optical electrophysiology to understand the neuron network dynamics and cellular biophysics in the live mouse brain. Together\, these molecular and optical methods will greatly expand our ability to decipher the brain. \nZoom link if unable to attend in person: https://ubc.zoom.us/\nMeeting ID: 93751 402493\nPasscode: 402493 \nFeedback survey for candidate
URL:https://www.centreforbrainhealth.ca/events/he-tian-candidate-presentation/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220228T153000
DTEND;TZID=America/Los_Angeles:20220228T170000
DTSTAMP:20260501T143539
CREATED:20220210T231708Z
LAST-MODIFIED:20220415T003557Z
UID:8219-1646062200-1646067600@www.centreforbrainhealth.ca
SUMMARY:Round Table: Cluster Member Introductions & Research Plans
DESCRIPTION:This month\, the Mental Health and Addictions IRP will be having a round table where each group member introduces themselves\, an overview of their research\, and their hopes and dreams for future collaborative research. \nZoom link if unable to attend in person: https://ubc.zoom.us/j/5747966049?pwd=N1ppY2tUS3o4bk9vTkFSTzBna3k0Zz09\nMeeting ID: 574 796 6049\nPasscode: 052059
URL:https://www.centreforbrainhealth.ca/events/mental-health-round-table-introductions-research-plans/
LOCATION:DMCBH Room 3402\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Monthly Monday Rounds in Mental Health and Addictions
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