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X-WR-CALNAME:Djavad Mowafaghian Centre for Brain Health | DMCBH
X-ORIGINAL-URL:https://www.centreforbrainhealth.ca
X-WR-CALDESC:Events for Djavad Mowafaghian Centre for Brain Health | DMCBH
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DTSTART;TZID=America/Vancouver:20261002T110000
DTEND;TZID=America/Vancouver:20261002T120000
DTSTAMP:20260818T162553Z
CREATED:20260326T202914Z
LAST-MODIFIED:20260818T162553Z
UID:17659-1790938800-1790942400@www.centreforbrainhealth.ca
SUMMARY:Dr. Deblina Sarkar: Circulatronics: Surgery-Free Neural Implants for Focal Brain Stimulation
DESCRIPTION:Bioelectronic implants for brain stimulation provide critical tools for treating brain diseases as well as investigating fundamental biology but require invasive surgery. In this talk I will discuss a new class of implants which we named Circulatronics: wherein intravenously introduced bioelectronic devices travel through the body’s global internal roadways i.e.\, the circulatory system\, and autonomously implant (without any external guidance) in the target brain region\, circumventing the need for any surgery. I will present how this enables targeted focal neuromodulation of deep brain regions in rodents. To achieve this\, we built subcellular-sized wireless energy harvesting electronics with high power conversion efficiency and integrated them with cells to create unique cell-electronics hybrids. Thus\, we fused electronic functionality with the biological transport and targeting capabilities of living cells. This technology can form the foundation for autonomously implanting bioelectronics with unprecedented access to the human body without surgery\, opening new avenues for healthcare and research.
URL:https://www.centreforbrainhealth.ca/events/dr-deblina-sarkar/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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DTSTART;TZID=America/Vancouver:20261019T110000
DTEND;TZID=America/Vancouver:20261019T120000
DTSTAMP:20260818T162154Z
CREATED:20260211T175922Z
LAST-MODIFIED:20260818T162154Z
UID:17396-1792407600-1792411200@www.centreforbrainhealth.ca
SUMMARY:Dr. Yulong Li: Quantitative imaging of neuromodulator dynamics in vivo by constructing new GRAB sensors
DESCRIPTION:The human brain comprises billions of neurons that communicate primarily through chemical synapses by releasing diverse neuromodulators\, which regulate perception\, movement\, learning\, and memory. Dissecting the neural mechanisms in both physiology and disease requires precise in vivo monitoring of neuromodulator dynamics. In the past few years\, we and others have developed a series of GPCR-activation‒based (GRAB) sensors that enable high-resolution monitoring of extracellular neuromodulator dynamics in behaving animals. Here\, I will present our latest GRAB sensors featuring large fluorescence lifetime changes\, which allow precise quantification of both phasic and tonic neuromodulator release. With these GRAB sensors\, we have monitored the dynamics of neuromodulators in mice in a wide range of physiological processes (reward\, motion\, etc.) and pathological conditions (Parkinson’s disease\, etc.).
URL:https://www.centreforbrainhealth.ca/events/dr-yulong-li/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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DTSTART;TZID=America/Vancouver:20261023T110000
DTEND;TZID=America/Vancouver:20261023T120000
DTSTAMP:20260326T204056Z
CREATED:20260326T204056Z
LAST-MODIFIED:20260326T204056Z
UID:17669-1792753200-1792756800@www.centreforbrainhealth.ca
SUMMARY:Dr. Michael J. Strong
DESCRIPTION:
URL:https://www.centreforbrainhealth.ca/events/dr-michael-j-strong/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20261030T110000
DTEND;TZID=America/Vancouver:20261030T120000
DTSTAMP:20260819T202117Z
CREATED:20260326T203619Z
LAST-MODIFIED:20260819T202117Z
UID:17665-1793358000-1793361600@www.centreforbrainhealth.ca
SUMMARY:Dr. Adrien Peyrache: Orienting memory during wake and sleep
DESCRIPTION:The head-direction (HD) circuit\, an upstream provider of orientation signals for navigation\, maintains coherent internal orientation memory that stays stable within each environment for weeks. During non-REM sleep\, when hippocampal trajectories are replayed for memory formation\, HD cells remain coordinated and directly influence this hippocampal replay. This suggests the HD system conveys a “virtual” orientation signal to support memory replay\, with the thalamus appearing to play a crucial role in generating it. Overall\, the HD system supplies the hippocampus and associated structures with a coherent\, possibly lifelong-stable signal maintained across brain states to support spatial navigation and memory formation.
URL:https://www.centreforbrainhealth.ca/events/dr-adrien-peyrache/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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