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X-WR-CALDESC:Events for Djavad Mowafaghian Centre for Brain Health | DMCBH
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DTSTART;TZID=America/Vancouver:20250207T110000
DTEND;TZID=America/Vancouver:20250207T120000
DTSTAMP:20260503T165206
CREATED:20240314T172306Z
LAST-MODIFIED:20250102T192407Z
UID:13060-1738926000-1738929600@www.centreforbrainhealth.ca
SUMMARY:UBC Kickstart Updates
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258
URL:https://www.centreforbrainhealth.ca/events/ubc-kickstart-updates-2/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20250214T110000
DTEND;TZID=America/Vancouver:20250214T120000
DTSTAMP:20260503T165206
CREATED:20240502T163317Z
LAST-MODIFIED:20250114T183541Z
UID:13294-1739530800-1739534400@www.centreforbrainhealth.ca
SUMMARY:Dr. Dorothy Schafer: Microglia-astrocyte crosstalk governing synapse remodeling
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nMicroglia and astrocytes have been implicated in remodeling synapses\, but whether and how these cells coordinate to remodel synapses remain open questions. Here\, we have identified key mechanistic underpinnings by which microglia instruct astrocytes to modify their synaptic coverage to enable synapse removal. We are further identifying how the degree of astrocyte synapse ensheathment can dictate windows of plasticity to enable microglia-mediated synapse remodeling in health and disease.
URL:https://www.centreforbrainhealth.ca/events/dr-dorothy-schafer/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20250221T110000
DTEND;TZID=America/Vancouver:20250221T120000
DTSTAMP:20260503T165206
CREATED:20240326T182656Z
LAST-MODIFIED:20250102T192603Z
UID:13117-1740135600-1740139200@www.centreforbrainhealth.ca
SUMMARY:Dr. Caroline Menard: Neurovascular adaptations underlie stress vulnerability vs resilience in mice and human depression
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nOur research program aims to shed light on the biological mechanisms underlying stress vulnerability vs resilience\, with help of state-of-the-art photonic technology\, in order to develop innovative treatments and identify biomarkers of mood disorders. Our multidisciplinary approach combines behavioral experiments to functional\, cellular\, molecular\, and imaging studies and validation of our rodent findings in human samples. We showed that chronic stress exposure promotes blood-brain barrier hyperpermeability leading to passage of circulating inflammatory mediators into the brain and the establishment of depressive behaviors. These changes occur in a sex-specific manner which may contribute to sex differences in depression prevalence\, symptoms and treatment responses. \n 
URL:https://www.centreforbrainhealth.ca/events/dr-caroline-menard/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20250227T110000
DTEND;TZID=America/Vancouver:20250227T120000
DTSTAMP:20260503T165206
CREATED:20241205T191009Z
LAST-MODIFIED:20250219T001550Z
UID:15024-1740654000-1740657600@www.centreforbrainhealth.ca
SUMMARY:Dr. Beatriz Rico and Dr. Oscar Marin
DESCRIPTION:Speaker: Dr. Beatriz Rico\, King’s College London \nTitle: Assembly of cortical neurons in a dynamic circuit \nIn our daily life\, animal behaviours rely on precise connectivity between neurons in the brain that can be modulated by experience. In the mammalian cerebral cortex\, these connections reach an extraordinary complexity. How are these cortical circuitries built? How they respond to activity and what happens when they fail during development are questions that we are currently addressing in my lab. In this seminar\, I will focus on the precise integration of diverse neuronal populations during development\, regulated by intrinsic molecular mechanisms and dynamic fine-tuning mechanisms that maintain the balance between excitation and inhibition. For instance\, the development of excitatory pyramidal cells is simultaneously and precisely counterbalanced by the formation of inhibitory synapses during the maturation of neuronal circuits. Although this process relies on neuronal activity\, different types of pyramidal cells likely respond to changes in activity through the expression of cell-specific genes. \n  \nSpeaker: Dr. Oscar Marin\, King’s College London \nTitle: Maturation and plasticity of cortical interneurons \nGABAergic interneurons play crucial roles in regulating neuronal activity in the cerebral cortex. A hallmark of cortical interneurons is their remarkable structural and functional diversity\, yet the molecular determinants and the precise timing underlying their diversification remain largely unknown. The search for mechanisms controlling the diversity of GABAergic interneurons has primarily focused on transcriptional programs driving the initial specification of different types of interneurons. However\, relatively little is known about the mechanisms regulating their terminal differentiation. In this talk\, I will describe molecular mechanisms controlling the maturation and plasticity of PV+ interneurons\, a subclass of cortical interneurons that is particularly vulnerable across a broad spectrum of psychiatric disorders. \n\nZoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258
URL:https://www.centreforbrainhealth.ca/events/dr-beatriz-rico-and-dr-oscar-marin/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20250228T110000
DTEND;TZID=America/Vancouver:20250228T120000
DTSTAMP:20260503T165206
CREATED:20240408T193919Z
LAST-MODIFIED:20250116T190243Z
UID:13197-1740740400-1740744000@www.centreforbrainhealth.ca
SUMMARY:Dr. Boris Heifets: Psychedelics\, anesthesia and dreaming
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nIn this lecture\, I will discuss our group’s efforts to deconstruct the psychedelic ‘state’\, drawing on both human and mouse experiments. While dreaming\, anesthesia and psychedelics are often considered distinct\, I argue that they share an underlying physiology\, phenomenology and possibly therapeutic effect.
URL:https://www.centreforbrainhealth.ca/events/dr-boris-heifets/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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