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X-WR-CALNAME:Djavad Mowafaghian Centre for Brain Health | DMCBH
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X-WR-CALDESC:Events for Djavad Mowafaghian Centre for Brain Health | DMCBH
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DTSTART;TZID=America/Vancouver:20250117T110000
DTEND;TZID=America/Vancouver:20250117T120000
DTSTAMP:20260503T183336
CREATED:20240927T212841Z
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UID:14592-1737111600-1737115200@www.centreforbrainhealth.ca
SUMMARY:Dr. Ami Citri: Cocaine to Volition: A research arc driven by automated behavioral analysis
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nI will discuss unpublished projects exploring the circuit basis of action selection\, describing how in-house development of an automated tool for behavioral annotation modified our research arc. Starting from cocaine-driven stereotypic actions\, we are exploring the neural circuit basis of involuntary and spontaneous actions\, and developing a framework for studying the neural circuit basis of volition.
URL:https://www.centreforbrainhealth.ca/events/dr-ami-citri/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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DTSTART;TZID=America/Vancouver:20250124T110000
DTEND;TZID=America/Vancouver:20250124T120000
DTSTAMP:20260503T183336
CREATED:20240722T194917Z
LAST-MODIFIED:20250102T192339Z
UID:14113-1737716400-1737720000@www.centreforbrainhealth.ca
SUMMARY:Dr. Florian Engert:  Focus versus Competence: Attentional Switching in Larval Zebrafish
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258\n\nDecision making strategies in the face of conflicting or uncertain sensory input have been successfully described in many different species.  Here we analyze large behavioral datasets of larval zebrafish engaged in a ‘coherent dot’ optomotor assay. We find that animal performance is bimodal and can be separated into two ‘states’\, an engaged state where performance is high and fish consistently turn into the direction of the coherent motion\, and a second\, disengaged state\, where performance drops to chance. We find that a simple HMM is sufficient to model these transitions and fits our experimental data well. We find that this addition can be incorporated into an existing DDM framework that has previously been used to model perceptual decision making in larval zebrafish. Further\, we leverage the large behavioral data sets to fit a mixture model of performance distributions and extract two latent variables which we term ‘focus’ and ‘competence’. Whereas ‘competence’ quantifies performance while the fish is in the engaged state\, the ‘focus’ variable captures the relative duration for which each animal persists in the engaged state. We show that ‘focus’ may be largely inherited from the parents\, while ‘competence’ is more likely to be influenced by environmental context. This quantitative framework for analyzing decision making can be used to screen genetic perturbations for their impact on these two aspects of performance\, and potentially help to identify a genetic basis\, and a neural mechanism for attention\, that extends across organisms.
URL:https://www.centreforbrainhealth.ca/events/dr-florian-engert/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20250131T110000
DTEND;TZID=America/Vancouver:20250131T120000
DTSTAMP:20260503T183336
CREATED:20240328T170932Z
LAST-MODIFIED:20250102T192427Z
UID:13160-1738321200-1738324800@www.centreforbrainhealth.ca
SUMMARY:UBC Kickstart Updates
DESCRIPTION:Zoom option if unable to attend in person:\nZoom link here (click on “Join a meeting”)\nMeeting ID: 91512 289258\nPasscode: 289258
URL:https://www.centreforbrainhealth.ca/events/ubc-kickstart-updates-3/
LOCATION:Rudy North Lecture Theatre\, Djavad Mowafaghian Centre for Brain Health\, 2215 Wesbrook Mall\, Vancouver\, British Columbia\, V6T 1Z3\, Canada
CATEGORIES:Neuroscience Research Colloquium
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